AI & I

Learn how the smartest people in the world are using AI to think, create, and relate.

Episode 13

Can Gemini 1.5 Pro Beat Our Best Stock Trade?

I sit down with investor Jesse Beyroutey to try to find the next Nvidia—with AI

Episode 39

His GPT Wrapper Has Half a Million Users—And Keeps Growing

Vicente Silveira on how lean startups can win big with AI

Episode 41

Do 60-minute Coding Tasks in 60 Seconds—With AI

Val Town's Steve Krouse on how far AI has come in the last year

Episode 27

Dwarkesh Patel’s Quest to Learn Everything

How the star podcaster uses AI tools to compound his own intelligence

Episode 44

An Inside Look at Building an Email Client in Three Months

With one engineer—and AI

Episode 14

How to Run a Profitable One-person Internet Business Using AI

Ben Tossell shows us the future of building businesses online

Episode 47

Vercel’s Guillermo Rauch on What Comes After Coding

As AI writes code, developers must become better product thinkers

Episode 27

Transcript: ‘Dwarkesh Patel’s Quest to Learn Everything’

‘AI & I’ with the star podcaster

Inside the Pod: Can AI Solve the Adult Friendship Problem?

New York Times columnist Kevin Roose made 18 AI friends to find out

Exclusive Analysis of ‘How Do You Use ChatGPT?’ With Logan Kilpatrick

Plus a transcript of the latest episode

Episode 49

He Built an AI Audience Simulator. It’s the Future of Customer Research.

Prompt engineer Michael Taylor created a tool that simulates real audience feedback—without the risk

Exclusive Analysis of ‘How Do You Use ChatGPT?’ With Anne-Laure Le Cunff

Plus a transcript of the latest episode

Episode 1

Introducing ‘How Do You Use ChatGPT?’

How the most interesting people in the world use ChatGPT to think, create, and grow

Episode 40

How We Incubate and Launch New Products With AI

What happens when you mix media, software, and AI—and how it’s going so far

Episode 10

Transcript: ‘How to Find Your Next Big Idea Hiding on the Internet’

‘How Do You Use ChatGPT?’ with Steph Smith

A Guide to Lifelong Learning—With AI

Dwarkesh Patel and Simon Eskildsen on their motivation to learn, curating information, and the spaced repetition method

Inside the Pod: Build a Six-figure Side Hustle in One Weekend

ChatPRD creator Claire Vo on how AI is making entrepreneurship accessible

Episode 13

Transcript: Can Gemini 1.5 Pro Beat Our Best Stock Trade?

‘How Do You Use ChatGPT?’ with Jesse Beyroutey

Episode 50

You Don’t Need More Money—Just A Better AI Strategy

Investor Mike Maples on how you can compete with OpenAI

Episode 12

Transcript: How a Hollywood Director Uses AI to Make Movies

‘How Do You Use ChatGPT?’ with Dave Clark

Episode 36

Transcript of ‘How Union Square Ventures Built an AI Brain for Venture Capital’

‘AI & I’ with Matt Cynamon

How to Use ChatGPT to Set Ambitious Goals

I followed Dr. Gena Gorlin’s prompts and had a breakthrough

Episode 32

The Browser Company Is Building a Brand That Drives Viral Growth

Head of storytelling Nashilu Mouen-Makoua on how to tell memorable stories

Episode 73

He’s Building the Plumbing For AI to Use the Internet

Stainless founder Alex Rattray on MCP, a protocol giving LLMs the tools they need to do real work